If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. Is Pyruvic acid good for my skin? Some substance identifiers may have been claimed confidential, or may not have been provided, and therefore not be displayed.

More information about Classification and Labelling is available in the Regulations section of ECHA website. ECHA has no public registered data indicating whether or into which articles the substance might have been processed. This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. It can also be used to construct the amino acid alanine and can be converted into ethanol or lactic acid via fermentation. These notifications can be provided by manufacturers, importers and downstream users. When information is available in all sources, the first two are displayed as a priority. The information is aggregated from the data coming from REACH substance registrations provided by industry. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. ECHA organises consultations to get feedback from all interested parties and to gather the widest possible range of scientific information for the regulatory processes.
The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. The Waste Framework Directive aims to protect the environment and human health from the generation and management of waste and to improve efficient use of resources. For example, an average-size red apple contains approximately 450 milligrams. PubChem- Open Chemistry Database. Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). Structure, properties, spectra, suppliers and links for: Pyruvic acid, 127-17-3. The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. Wang X. Substances for which classification and labelling data have been notified to ECHA by manufacturers or importers.
Pyruvic acid – Mechanism of Action. If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. Substances predicted as likely to meet criteria for category 1A or 1B carcinogenicity, mutagenicity, or reproductive toxicity. ECHA has no public registered data indicating whether or in which chemical products the substance might be used. Der analytische Nachweis kann mit Phenylhydrazin, α- oder β-Naphthol oder 2,4-Dinitrophenylhydrazin durchgeführt werden. Sodium pyruvate is a salt of the conjugate anion form of pyruvic acid, known as pyruvate.It is commonly added to cell culture media as an additional source of energy, but may also have protective effects against hydrogen peroxide.This was reported by Giandomenico et al. Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. Biocidal Products Committee opinions on active substance approval, National authorisation and mutual recognition, Understanding the Waste Framework Directive, Tools to prepare and submit SCIP notifications, List of substances subject to the POPs Regulation, Draft recommendation for inclusion in the Authorisation List and consultation, Submitted restrictions under consideration, Harmonised classification and labelling targeted consultations, Consultations on ECHA Executive Director’s requests, PACT - Public Activities Coordination Tool, Information on Candidate List substances in articles, Candidate List of substances of very high concern for Authorisation, Registry of restriction intentions until outcome, Registry of SVHC intentions until outcome, Table of harmonised entries in Annex VI to CLP, Occupational exposure limits - Activity list, Harmonised classification and labelling (RAC), Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Guidance on the safe use of the substance, Annex III: criteria for 1 - 10 tonne registered substances, Previous consultations on ECHA’s Executive Director Requests to the Committees, Applications for authorisation consultations, Harmonised classification and labelling consultations, ECHA Executive Director’s requests related to the CLH process, Consultation on potential candidates for substitution, Consultation on derogation to the exclusion criteria, ECHA's Executive Director Requests to the Committees, Consultation on a draft recommendation for amendment of Authorisation List entries, Consultations in the authorisation process, Occupational exposure limits - Call for comments and evidence, Occupational exposure limits - Previous calls for comments and evidence, Occupational exposure limits – Consultations on OEL recommendation, Derogations for the protection of cultural heritage, ECHA's current activities on restrictions, ECHA's completed activities on restriction, Information on Candidate List substances in articles table, Information from the Existing Substances Regulation (ESR), PBT/vPvB assessments under the previous EU chemicals legislation, Adopted opinions and previous consultations on applications for authorisation, Adopted opinions on restriction proposals, Mapping exercise – Plastic additives initiative, Occupational exposure limits substance evaluations, List of substances subject to POPs Regulation, Small and Medium-sized Enterprises (SMEs), Practical examples of chemical safety reports.

the electronic edition of the Official Journal of the European Union. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information. Methylglyoxylate. Pyruvic acid, as with all AHAs, improves skin texture and reduces the signs of aging by promoting cell shedding in the outer layers of the epidermis and by restoring hydration. In der Biochemie bezeichnet Pyruvat das Anion der Brenztraubensäure und ist ein C-3-Körper. What is Pyruvate? The peeling action of  Pyruvic acid at 50% has been described as similar in effect to the more popular Salicylic acid at 30%4.

Kornhauser A, Coelho S, Hearing V. Effects of cosmetic formulations containing hydroxy. The mechanism of action is not completely understood. This substance is used for the manufacture of: chemicals. This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance): Welcome to the ECHA website.

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